Bethesda: "Ome" Sweet "Ome"—Epigenome Joins Genome, Proteome
Histone acetylation is a particularly intriguing epigenetic mark, in part because it changes dynamically...
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Histone acetylation is a particularly intriguing epigenetic mark, in part because it changes dynamically...
CLU, CR1, and PICALM emerge again as late-onset AD risk genes in a large case-control association study...
Conventional wisdom says that Down syndrome (DS) goes hand-in-hand with intellectual disability—but what if that was not true?...
A growing body of evidence agrees that FAD-PS mutants are connected to dysregulated calcium signaling in the brain...
Methylation patterns being strongly influenced by the genetic makeup of the individual was taken up at the workshop...
Voltage-gated calcium channels swing open with passing action potentials, allowing calcium ions into the cell, and slide shut when the membrane depolarization has passed...
A study found that after two years, AD patients on a comprehensive care plan fared no better than study participants receiving standard care at memory clinics...
Occam’s razor, as the maxim is now known, may not cut it every time, but as applied to γ-secretase...
Epigenetics, the study of how modifications to DNA and chromatin regulate the activity of genes, is the hot new thing in bioscience...
PatientsLikeMe reports that its users found benefits including enhanced understanding of their symptoms and side effects of medication...
Clustering around synthetic Aβ oligomers embedded in the cell membrane, metabotropic glutamate receptors unleash an influx of calcium that is toxic to neurons...
Researchers propose that several-fold increases of α-synuclein can trigger a slew of pathological changes leading to synaptic dysfunction...
Toxic marine algae can cause oceanic dead zones, suffocation in fish, insanity in marine mammals—and perhaps, neurodegenerative disease...
Researchers report that Bcl-2, normally a pro-survival protein, turns bad when it hooks up with SOD1...
Like thermostats that switch on heating or cooling to regulate temperature, neurons tune their excitability up or down to weather environmental changes...